Cases of Acromegaly

Curious cases: Acromegaly and schizophrenia: an incidental association?

OBJECTIVE Acromegaly associated to schizophrenia was first reported ~60 years ago, and so far, it is unclear whether this association is causal or not. Our aim was to report new cases with both clinical entities and to discuss the potential pathophysiological mechanisms of this association. METHODS Three new cases and data from literature are reviewed. RESULTS We report 2 males and 1 female...

Acromegaly

Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic, cardiovascular, respiratory, and metabolic...

Acromegaly

Acromegaly is a comparatively rare disease but has attracted the notice of clinicians all over the world on account of the peculiar features associated with it. Within recent years, the finding of an adenomatous growth in the pituitary gland in cases of acromegaly lias focussed a great deal of interest around the subject. This monograph of Dr. Atkinson is therefore likely to be well received by...

Acromegaly.

Familial acromegaly - case study of two sisters with acromegaly.

In the majority of cases, acromegaly is sporadic. However, it can also occur in a familial setting as a component of MEN-1, MEN-4, Carney complex (CNC) or as the extremely rare syndrome of isolated familial somatotropinoma (IFS), the latter belonging to familial isolated pituitary adenomas (FIPA). The diagnosis of IFS is based on the recognition of acromegaly/gigantism in at least two family me...